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TestubesThe Naval Blood Research Laboratory (NBRL), under the direction of C. Robert Valeri, M.D. (Capt, MC, USNRet) was once a U.S. Navy laboratory, a government-owned, contractor-operated facility and is now known as NBRL, Inc. The mission of the laboratory is now and always has been to develop blood products and methods to treat military and civilian casualties. Funding for the laboratory in the past has been provided primarily by grants from the Navy's Bureau of Medicine and Surgery and Office of Naval Research (ONR) as well as the U.S. Congress.

Haemonetics Model 215Major accomplishments over the years include developing the procedure to freeze red blood cells with glycerol, obtaining FDA approval for this red blood cell freezing procedure, obtaining FDA approval for rejuvenating both indated and outdated red blood cells using the NBRL-developed PIPA solution, obtaining FDA approval to prolong the storage of fresh frozen plasma from 1 year to 7 years, obtaining FDA approval for an automated, closed system (the Haemonetics ACP215) to glycerolize and deglycerolize red blood cells to allow for an extension of the post-wash storage period from 1 day to 2 weeks, and the submission of data to obtain FDA approval for DMSO-frozen platelets.

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The NBRL is currently planning research in collaboration with the U.S. Army to evaluate a new method to freeze platelets with DMSO and a new resuscitative solution containing ketones which may potentially be used to treat wounded servicemen.

Funding from the laboratory comes from NBRL’s response to requests for proposals from government and non-government sources.

© 2003 Naval Blood Research Laboratory
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